In the second section on biohacking, we're gonna be talking about a particular nootropic, called alpha GPC. And also CDP, which in essence is a cooling molecule that's tied together with glycerol phosphate, it just helps to increase absorption. I don't want to belabor the biochemical part of this, but it's important to know because if you're spending money on nootropics, you want to get something that actually has been shown to have some benefit. And not just, you know, wasting money on supplements that are, they're useless. So how it works, in essence is that cooling is turned into acetylcholine inside the brain, and it crosses the blood brain barrier, which is important. You need to have a chemical that's able to get across that membrane into the brain where it works.

Having it in the gut and other parts of the body is not going to improve your memory test taking cognition, executive function, or any of those things that are critical in terms of beneficial effects of nootropics. And so within an hour of taking The Alpha GPC it actually shows up inside the brain. And it peaks about two to three hours after ingestion by taking a proper form of the colon, particularly when it's complex to fossa, title colon, or alpha GPC. It actually is 12 times more vile bioavailable, so that means it actually can do the job that it's designed to do of interest that Alzheimer's disease and other degenerative neurologic disorders at their core have a problem with acetylcholine, particularly decreased levels of acetylcholine or just not functioning properly. And that stimulated a huge amount of interest in the research community and medical community as well in terms of studies and data on how alpha GPC can actually work.

And so, just sharing some of the potential benefits of alpha GPC is that it can increase and improve cognitive enhancement, boost memory, reading Call and performance. For the athletes out there it's actually been shown to increase strength and power and athletes. In terms of brain health and longevity. It provides a level of neuro protection and is used in the treatment of stroke, Alzheimer's and other types of dementia. And it's also been shown to boost and elevate the mood is similar to the lion's mane, or the mo Boucher Takia that I talked about in the first segment of the section. There are some natural sources of alpha GPC including red meat, organ tissue, lesser degree plant sources, I've got these all detailed on the blog, and a nicely chronicled list there that I got from another source.

It's also found primally supplements and that's how I particularly rely on alpha GPC in terms of enhancing cognitive function for particular needs was writing or taking a test variety of other uses for it. Please note that CDP Coleen even though it is calling in alpha GPC, they're not the same CDP calling which is Probably a less expensive one found in some nootropics it actually is weaker in terms of the nootropic properties. The data on CDP Colin, it's actually been primarily used more in younger patients who've got some baseline cognitive deficits. So in a nutshell, how works is it basically is helping to produce and upregulate or stimulate a variety of neurotransmitters, including dopamine, acetylcholine and serotonin. There's also some benefit in terms of synergy where one plus one equals more than two. So in essence, we're alpha GPC taken with caffeine or some of the acid Tam such as Prasad Tam, actually have shown enhanced effects.

There's an interesting study human study where when they split those up into three different doses, actually improve the cognitive performance and also slow the cognitive decline in older patients such as Alzheimer's patients who have memory problems. The other cool thing about alpha GPC particularly, you know if you're a young college student, somebody who's interested in fitness and working out, it actually reduces reaction times and present prevents mental exhaustion after intense exercise. So, myself, I'm into triathlon and endurance events and anything that can help with that mental side of things, particularly GPC in some amino acids also have that same beneficial effect. So how should it be taken in terms of what's out there in the literature, you're going to find doses as small as 300 per day, all the way up to 1200 milligrams per day. Single versus divided dose, I think it depends particularly what you're intending to use it for.

But keep in mind that the peak effect is in about two to three hours for most people, and the duration to a lesser extent can be seen all the way out to 24 hours. There are some side effects probably similar to what can be seen with a variety of other medications including placebos, such as headache, fatigue, anxiety, nervousness, upset stomach gi distress cramps, for some subpopulation can result in dizziness and low blood pressure. Again, it's purely about common sense. consulting your personal physician if you have some concerns underlying health problems or are taking already prescription medications, it's all about common sense and being safe. But there are certainly some clear benefits to nootropics. In part three, I'll be talking about some critical elements about how long term your use of nootropics can affect their efficacy and the results that a person might experience.