When we first pass the 12 hour mark, there are significant changes happening within our metabolism. The balance between ketone production, glucose and other compounds is such that the body starts to promote its own healing. The chart shows the ketone production takes off at the 12 hour mark. So making more fuel available for the cells to create energy. At the same time, glycogen, a tissue repair hormone also increases. Insulin drops to a new lower level.
As glucose falls. Over a 24 hour fasting period, ketone production continues to rise We can see that when we wake in the morning, and soon eat breakfast, we break the fast, which means that we stopped the process called autophagy from just starting fasting for 18 hours, say from the evening meal to lunchtime the next day is a great benefit. And 24 hour fast is even more effective because of the 16 hour mark, or toffee g kicks in. When a cell burns sugar, certain toxic byproducts, either hanging around in the cells, or are expelled into the bloodstream. In either case, they can cause problems. In and around the cell.
They reduce the amount of oxygen available, which is essential for cell respiration. They also promote inflammation in soft tissues fed by the blood cells. Even a healthy cell can produce malformed DNA, and other bio compounds that are simply no use at all. When the mitochondria become damaged, because of a high carb diet, they become even less efficient, creating more and more waste products. These waste products must be removed before they can cause damage. Fortunately, there's a natural process called autophagy, which does exactly that.
Autophagy literally means self eating. And the mechanism was described by a Japanese researcher, Yoshi Amman or Xiaomi, who won the Nobel Prize in 2016. autophagy is triggered by fasting. So it's very relevant to this lecture when there isn't enough glucose or Qi tolls to burn ourselves do two things. They burn stored fat, and also digest our own biological waste, ie unfinished proteins and dead cell parts that are no longer needed. It's a great way to clean the body and make us healthier. Without autophagy biological waste products are swept along the bloodstream, and sometimes they stick on the Ontario walls.
They can be absorbed into the tissues causing inflammation, and other problems. The brain in particular, is a kind of a garbage dump for unwanted waste products. These can cause Alzheimer's, Parkinson's disease, dementia, and other problems with cognitive processes. The body's circulatory system is in credibly complex and contains about 100,000 kilometers of blood vessels. Over 30,000 kilometers of these are tiny Caterpillar is so small as a single blood cell was folded into before passing through. It's very easy to see that unwanted waste products can cause problems in these narrow tubes by blocking them or making them much less efficient.
Using fasting to induce autophagy is a very important part of changing over to a keto diet.