So quick overview, too many carbohydrates leads to too much insulin. Too much insulin leads to insulin resistance. And too much insulin also leads to a redirection of the other amino acids away from the blood brain barrier. This means too much tryptophane crosses the blood brain barrier. And this of course, means too much serotonin is produced and there are signs and symptoms of insulin resistance. The signs and symptoms of insulin resistance are barely fat, and high fasting blood sugar.
In other words, when you measure your blood sugar using a glucometer, the measurement is above 5.55 and below is really optimal. Poor sleep patterns, carbohydrate cravings at anytime but very very often in the mid to late afternoon. And sugar lows hypoglycemia When your blood sugar drops, and then you don't feel good. So, giving SSRIs tryptophan or five HTP, in order to assist in depression and mood disorders may not help if you have blood sugar dysregulation and your insulin resistance because the insulin resistant is going to really rubbish the whole system