So, in conclusion, with the invention of the microscope, and the observation of microorganisms by hook, the interest in the world of microscopic organisms were sparkled. Lewin hook, call these micro organisms as animal skills. In trying to understand the origin of living organisms, there began a controversy over spontaneous generation, which then initiated the need for accurate scientific experimentation. That experiments in turn, then help this spell this concept. Jenner tested prevention against diseases with the intentional vaccination of a boy with vaccine virus which made immune to the small pox virus. Semmelweis used chlorinated water for hand washing, thus helping to decrease disease transmission.
And Lister used phenol for wounds and surgical incisions, helping reduce the rate of death due to infections. Also, Nightingale introduced better hygienic conditions, which then led to better health conditions and snow emphasize the importance of water sanitation and introduced the field of epidemiology. Finally, Ehrlich invented a magic bullet aimed at specific microorganisms leaving healthy cells unharmed, advancing the field of chemotherapy. The classical golden age range from eight 54 to 1914 during this period with the understanding that specific diseases are caused by specific microorganisms, faster propose the germ theory. This was also the time that pastor had disproved spontaneous generation. Robert Kok was able to prove the germ theory by conducting an experiment with the anthrax pasilla.
He summarized certain criteria to determine the specificity of the pathogen to the disease, which then led to his postulates. Other scientists worked on diseases caused by what was initially thought to be bacteria, but these microorganisms were shown to be filterable agents, and were called as virus a term coined from the Latin word poison. The second Golden Age data from 1943 till 1970. During this time the field of molecular biology had lost some DNA was experimentally shown to be the hereditary material in cells. With the use of electron microscope, two cell types eukaryotic and prokaryotic were discovered. During World War Two there was a great need for a mass production of antibiotics.
In the 1960s interest in the microbial world was fading away and resistance to antibiotics was beginning to surface. The third Golden Age began in 1970 and it lasts till the present time. This is the age of full fledged Shanti Arctic resistance with the existence of superbugs resistant to several oral antibiotics. Also, emerging diseases such as hantavirus, and reemerging diseases such as smallpox have been challenging the scientific and medical communities, by via mediation started making use of the beneficial effects of microorganisms that can degrade organic compounds. The use of biological weapons to cause terror has brought about caution in biomedical research. And finally, with the sequencing of the microbial genome, the study of microbial evolution has been made possible in a more detailed and in depth manner.
With this, we conclude section one the history of microbiology